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I don't think I've ever used a web front end layout framework and thought: wow, this really works. In fact, so far I have 100% of "for fucks sake…" as I scour through the source code for how it's supposed to be used.
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And it's worth acknowledging that the developers working on these frameworks have a (near) impossible job on their hands - which equally is the problem I tend to face: the framework is solving problems for the broadest audience.